Marcos Henrique Rosa
Ribeirão Preto
Summary
My background in molecular biology and immunology is complemented by nine years of experience in primary T cell cultures and autoimmune/inflammatory mouse models. I have honed my expertise in Treg regulation, and my adaptable and team-oriented nature allows me to excel in learning new techniques across diverse environments.
Overview
10
10
years of professional experience
Work History
Student Laboratory Assistant
University of São Paulo - Pain and Inflammation Lab
01.2018 - Current
- Company Overview: Research lab focused on pain and inflammation studies
- I have completed my master's and am pursuing a PhD focused on autoimmune diseases and regulatory T cells in inflammatory conditions, utilizing in vivo models
- Conducted metabolic assays with a focus on glycolysis using Seahorse technology
- My academic pursuits have equipped me with advanced expertise in various lab techniques, including ELISA, Western Blot, flow cytometry, primary lymphocyte culture, and CRISPRcas9 in primary T cells
- This comprehensive skill set instills confidence in my ability to contribute to the field of biomedical sciences
- Presenting research at national and international conferences
- Managed project development, lab supplies, and international collaborations
- Collected, interpreted, discussed, and presented scientific data effectively
- Reviewed manuscripts, protocols, and reports with attention to detail
- Demonstrated strong scientific communication skills during group meetings, lectures, and events
- Collaborated effectively with colleagues across various groups and departments, fostering a cooperative research environment
- Adaptable and quick learner, thriving in diverse laboratory settings
- Strong problem-solving abilities, with a focus on achieving ambitious research goals
- Research lab focused on pain and inflammation studies
Guest Researcher
Max Delbrück Center for Molecular Medicine
08.2023 - 08.2024
- Company Overview: Research center focused on molecular medicine and immunology
- Investigated the connection between autophagy and autoimmune diseases, leveraging the power of CRISPR in the manipulation of primary T lymphocytes
- Actively participated in meetings focusing on both basic and translational research in immunology
- Presented and attended international conferences, deepening scientific knowledge globally
- Collection, Interpretation, discussion, and presentation of scientific data
- Contributed significantly to the dissemination of research findings by writing and reviewing manuscripts, protocols, and reports
- Strong scientific communication skills at group meetings, lectures, and events
- Collaboration with colleagues from the same and different Groups/Departments
- Research center focused on molecular medicine and immunology
Student Laboratory Assistant
DNA Polymorphism and Molecular Immunopathology Lab
01.2015 - 01.2017
- Company Overview: Research lab focused on molecular immunopathology
- Worked on CXCR4 gene polymorphisms linked to medulloblastoma, using ELISA and flow cytometry to assess immune responses
- Involved in organizing and promoting scientific outreach activities
- Research lab focused on molecular immunopathology
Education
Pharmacology
University of São Paulo
Ribeirão Preto, Sao Paulo, Brazil03-2025
Master of Science - Immunology
University of São Paulo
03.2020
Bachelor of Science - Biomedicine
State University of Londrina
Londrina, Parana12.2017
MBA - Sales Management
University of São Paulo
São Paulo, Brazil06-2025
Skills
- Flow Cytometry
- Primary T Cells Culture
- CRISPR in Primary T cell culture
- Inflammation Mouse Models
- Breeding mice Cre-Lox
- EAE
- QPCR
- ELISA
- Sea Horse
- Western Blot
- GraphPad Prism
- Scientific Writing/Presentation
- Ability to Work in a Team
- Flexibility and Adaptability
- Microsoft Office
- Strong Communication Skills
- Project Manager
- Microsoft Excel
Personal Information
- Title: MSc. in Immunology and PhD in Pharmacology candidate, researcher
- Date of Birth: 03/16/93
- Nationality: Brazilian
Languages
Portuguese - Native.
English - Fluent.
Spanish - Intermediate
German - Beginner.
Awards
- 2022, Honorable mention at IV Workshop on Inflammation and VII Inflammma of the Brazilian Society of Inflammation - PhD student
- 2024, Honorable mention at V Workshop on Pharmacology, FMRP, São Paulo University - PhD student
Publications
- Potential use of CXCL12/CXCR4 and Sonic Hedgehog pathways as therapeutic targets in medulloblastoma, Acta Oncologica, 2018, Amarante MK, Vitiello GAF, Rosa MH, Mancilla IA, Watanabe MAE
- PKM2 promotes Th17 cell differentiation and autoimmune inflammation by fine-tuning STAT3 activation, Journal of Experimental Medicine (JEM), 2020, ALVES DAMASCENO, LUIS EDUARDO, PRADO, DOUGLAS SILVA, VERAS, FLAVIO PROTASIO, FONSECA, MIRIAM M., TOLLER-KAWAHISA, JULIANA E., ROSA, MARCOS HENRIQUE, PUBLIO, GABRIEL AZEVEDO, MARTINS, TIMNA VARELA, RAMALHO, FERNANDO S., WAISMAN, ARI, ALVES, JOSÉ CARLOS
- Pitavastatin ameliorates autoimmune neuroinflammation by regulating the Treg/Th17 cell balance through inhibition of mevalonate metabolism, International Immunopharmacology, 2021, PRADO, D. S., DAMASCENO, L. E. A., SONEGO, A. B., ROSA, M. H., MARTINS, T. V., FONSECA, M. D. M., CUNHA, T. M., CUNHA, F. Q., ALVES-FILHO, J. C.
- Sepsis-Induced Immunosuppression Is Marked by an Expansion of a Highly Suppressive Repertoire of FOXP3+ T-Regulatory Cells Expressing TIGIT, The Journal of Infectious Diseases, 2022, Mikhael Haruo Fernandes de Lima, Carlos Hiroji Hiroki, Vanessa de Fátima Borges, Guilherme Cesar Martelossi Cebinelli, Jessica Santos, Marcos Henrique Rosa, Camila Meirelles S Silva, Carlos Wagner S Wanderley, Augusto Velozo Gonçalves, Gustavo Fernando Silva Quirino, Dario S Zamboni, Thiago M Cunha, José-Carlos A Filho, Fernando Q Cunha
- Macrophage-derived human resistin promotes perivascular adipose tissue dysfunction in experimental inflammatory arthritis, Biochemical Pharmacology, 2024, Aline G Fedoce, Flávio P Veras, Marcos H Rosa, Ayda H Schneider, Isadora M Paiva, Mirele R Machado, Edismauro G Freitas-Filho, Josiane F Silva, Caio C Machado, José C Alves-Filho, Fernando Q Cunha, Leandra N. Z. Ramalho, Paulo Louzada-Junior, Anthony S Bonavia, Rita C Tostes
- Mineralocorticoid receptor antagonism partially prevents dysfunction of T cell maturation in rats chronically treated with ethanol, Naunyn-Schmiedeberg's Archives of Pharmacology, 2024, Thales M. H. Dourado, Daniele C. Nascimento, Marcos H. Rosa, Victor O. Assis, Gustavo F. Pimenta, José C. Alves-Filho, Carlos R. Tirapelli
- The DNA sensor AIM2 mediates psoriasiform inflammation by inducing type 3 immunity, JCI Insight, 2024, Timna Varela Martins, Bruno Marcel Silva de Melo, Juliana E. Toller-Kawahisa, Gabriel V.L. Silva, Conceição E. Anibal-Silva, Isadora M. Paiva, Gabriel A. Publio, Marcos Henrique Rosa, Cacilda da Silva Souza, Dario S. Zamboni, Fernando Q. Cunha, Thiago M. Cunha, Bernhard Ryffel, Nicolas Riteau, José C. Alves-Filho
References
References available upon request
Timeline
Guest Researcher
Max Delbrück Center for Molecular Medicine
08.2023 - 08.2024
Student Laboratory Assistant
University of São Paulo - Pain and Inflammation Lab
01.2018 - Current
Student Laboratory Assistant
DNA Polymorphism and Molecular Immunopathology Lab
01.2015 - 01.2017
Master of Science - Immunology
University of São Paulo
Bachelor of Science - Biomedicine
State University of Londrina
Pharmacology
University of São Paulo
MBA - Sales Management
University of São Paulo
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